Search on: COMPLEMENT C2 FRAGMENT A 
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Descriptor English:   Complement C2a 
Descriptor Spanish:   Complemento C2a 
Descriptor Portuguese:   Complemento C2a 
Synonyms English:   C2a Complement
Complement 2a
Complement C2 Fragment a
Complement C2a Fragment
C2a Fragment, Complement
C2a, Complement
Complement, C2a  
Tree Number:   D12.776.124.486.274.150.500
Definition English:   The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated COMPLEMENT C1S. It is a SERINE PROTEASE. C2a combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE). 
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50825 
Unique Identifier:   D050678 

Occurrence in VHL:
 

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